Three folding engraved plates & one folding printed table. x, [11]-240 pp. 8vo, cont. vellum over boards (binding a little soiled & stained). Paris: F.A. Didot, 1775.

First edition. Troja (1747-1827), studied medicine at Naples and in 1774 he went to Paris where he began the research on the formation of bone tissue and bone generation which made him famous. Although Réaumur and Trembley had earlier demonstrated the regrowth of limbs in crustacea and polyps, no one before had considered the possibility of regrowth of bones.

“Troja demonstrated that if a foreign body is introduced into the marrow cavity of... More